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Neurotransmitter Receptor Influence on BehaviorNicotinic Acetylcholine Receptors StudyChemical synthesis and alkaloids

Novel 5,6-Bicyclic Compounds as 5-HT2A Receptor Agonists for Treating Depression, Anxiety, Substance Abuse, and Headaches

R. W. Sabnis, Anika R Sabnis

2026.6.3ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.6c00270

Abstract

Provided herein are novel 5,6-bicyclic compounds as 5-HT2A receptor agonists, pharmaceutical compositions, use of such compounds in treating depression, anxiety, substance abuse and headaches, and processes for preparing such compounds.

Citation format

SABNIS, R. W.; SABNIS, Anika R. Novel 5,6-bicyclic compounds as 5-HT2A receptor agonists for treating depression, anxiety, substance abuse, and headaches. ACS Medicinal Chemistry Letters, 2026, 17(7): 1451–1452.