Mathematical Biology Tumor GrowthGene Regulatory Network AnalysisMicro and Nano Robotics

A. Huang, Yifu Wang, Yuanyuan Ke

2026.6.8CSIAM Transactions on Applied Mathematics

DOI: 10.4208/csiam-am.so-2025-0102

Abstract

We study a chemotaxis model with signal-dependent motility and indirect consumption mechanism, described by a cross-degenerate parabolic system. The motility function $\phi (v)$ is assumed to behave as $v^\alpha$ near $v=0,$ leading to cross-degenerate diffusion. Under the presence of a logistic growth term in the cell dynamics, we establish the existence of globally bounded classical solutions provided the crowding coefficient b is sufficiently large. Moreover, for strongly degenerate cases $(\alpha>1),$ we prove uniform convergence of solutions toward the homogeneous steady state $(1/b,0,1/b)$ as $t→∞.$ Our analysis relies on the construction of a conditional energy functional and temporally averaged estimates, which enable us to overcome the difficulties induced by cross-degeneracy. Numerical simulations illustrate how variations in the parameter $b$ and the growth rate $\delta$ influence pattern formation, highlighting transitions from homogeneity to spatially heterogeneous structures.

Citation format

HUANG, A.; WANG, Yifu; KE, Yuanyuan. Global boundedness and asymptotic behavior in a chemotaxis-consumption model with signal-dependent motility and indirect sensing. CSIAM Transactions on Applied Mathematics, 2026.