Sex differences in documented clinical features of memory clinic patients: a natural language processing study

Highlights • Natural language processing was applied to 1036 routine memory clinic letters to examine sex differences in documented clinical features.• We found showed substantial overlap in documented clinical features between women and men, with modest differences in a small subset of features.• No sex differences remained statistically significant after correction for multiple comparisons.• Documented clinical features reflect a combination of symptom occurrence, patient reporting, and clinician documentation practices.• The study demonstrates the applicability of NLP for investigating documentation patterns in routine clinical data.