Qiu-Xiao Ren, Ya-Jin Liu, Ping Wang, Xiaowei Song, Qian Zhao, Yanan Cao, Ru‐Tai Hui, Huangtian Yang, Yi Zhu, Chunchun Wei, An-Jing Ren, Weiping J. Zhang
2026.4.9Acta Physiologica
tlooto Summary
This study seeks to clarify the molecular mechanism of PLN regulation and its functional relevance in cardiac physiology.
Abstract
Phospholamban (PLN) is a key regulator of sarco‐endoplasmic reticulum calcium ATPase (SERCA) activity and myocardial contractility, but its expression control remains incompletely understood. This study seeks to clarify the molecular mechanism of PLN regulation and its functional relevance in cardiac physiology.
Citation format
REN, Qiu-Xiao, et al. Mir‐221 mediates the regulation of phospholamban expression and cardiac contractility by ZBTB20. Acta Physiologica, 2026, 242(5): e70217.