ChemistryMedicine

Shake‐Induced Temporary Ion‐Pairing Between Lecithin and Glycolic Acid for Enhanced Exfoliation in a Novel Biphasic Serum: Comparative Ex Vivo and in Vivo Randomised Studies

K. Kwon, Mi Jung Kim

2026.4.1SKIN RESEARCH AND TECHNOLOGY

DOI: 10.1111/srt.70349

Abstract

Chemical exfoliation efficacy is significantly limited by pH‐dependent permeability reduction above the pKa of glycolic acid (3.83), constraining consumer product development.

Citation format

KWON, K.; KIM, Mi Jung. Shake‐induced temporary ion‐pairing between lecithin and glycolic acid for enhanced exfoliation in a novel biphasic serum: Comparative ex vivo and in vivo randomised studies. SKIN RESEARCH AND TECHNOLOGY, 2026, 32(4): e70349.