The increase in the prevalence of acne vulgaris and health policy aimed at improving the patients’ quality of life. Systematic review

Introduction: Acne vulgaris is a growing global public health concern with increasing prevalence across age groups and regions. Long-term management remains challenging due to the adverse effects of pharmacological treatments, antibiotic resistance, and insufficient integration of supportive skincare strategies. Aim: This study aimed to review the literature on the increasing prevalence of acne vulgaris and to assess the possibilities and limitations in selecting effective treatments. Materials and Methods: This systematic review was based on a qualitative meta-analysis of 66 peer-reviewed studies published between 2020 and 2025. The analysis focused on epidemiology, pharmacological treatments, adjunctive skincare approaches, and policy frameworks. Results: The findings indicate that acne prevalence has increased by more than 60% since 1990, with a rising burden among adults and populations in lower socio-demographic regions. Current treatments primarily rely on antibiotics, retinoids, and hormonal therapies, which are effective in the short term but have limitations. Conclusions: The study highlights the need for a dual approach that optimizes temporary pharmacological treatment while integrating skincare as a central component of long-term acne management. Such an approach can reduce dependence on antibiotics, improve patient outcomes, and align treatment strategies with broader public health objectives.