Medicine

Jiajin Lv, Xu Lin

2026.4.29OncoTargets and Therapy

DOI: 10.2147/ott.s586690

Abstract

Abstract Pregnancy-associated breast cancer (PABC) refers to newly occurring breast cancer from the beginning of pregnancy to within one year after delivery. In recent years, with changes in societal attitudes toward fertility, the number of women marrying and giving birth at older ages has steadily increased. The delay in the age of childbearing has gradually increased the risk of women being exposed to breast cancer during pregnancy, and thus the incidence of PABC has been on the rise. The treatment of PABC is challenging. The treatment plan should not only control the tumor progression of the patient but also ensure the healthy development of the fetus. Therefore, it is very important to formulate an individualized diagnosis and treatment plan. Thus, this article explores the diagnosis and treatment methods of PABC to respectively expound the feasibility and safety of the relevant diagnosis and treatment means in the first, second and third trimesters of pregnancy.

Citation format

LV, Jiajin; LIN, Xu. Advances in the treatment of breast cancer at different stages of pregnancy. OncoTargets and Therapy, 2026, 19: 1–13.