Medicine

Sara J. Judickas, Joseph R. Brown, R. Mendicino

2026.3.11JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION

DOI: 10.3390/japma116020012

Abstract

Venothromboembolic (VTE) events are considered rare complications following foot and ankle surgery. Most instances of VTE following surgical procedures occur in particularly high-risk patient populations; therefore, VTE prophylactic anticoagulation is initiated based on risk/benefit stratification for each individual patient undergoing foot and ankle surgery. We present a case report on a 40-year-old male who underwent isolated Lisfranc ligament repair and subsequently developed an acute saddle pulmonary embolism and deep vein thrombosis 1 month postoperatively. The patient was on prophylactic Lovenox, yet still developed a life-threatening complication. The patient was found to be on a selective estrogen receptor modulator for the off-label treatment of male infertility. This medication, surgical intervention, and a period of non-weight bearing are believed to be contributory to the patient's relatively increased hypercoagulable state. This case depicts a rare complication of foot and ankle surgery and highlights the importance of VTE prophylaxis during the postoperative period.

Citation format

JUDICKAS, Sara J.; BROWN, Joseph R.; MENDICINO, R. Saddle pulmonary embolism and deep vein thrombosis following foot and ankle surgery while on prophylactic lovenox: A case report. JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION, 2026, 116 2(2): 12.