BiologyMedicine

Brian Charlesworth

2026.3.6EVOLUTION

DOI: 10.1093/evolut/qpag035

tlooto Summary

Examination of random genetic drift and temporal fluctuations in fitness on loci maintained by balancing selection suggests ways in which substantial additive variance can be maintained, by causing loci to depart from their equilibria under selection alone.

Abstract

The existence of substantial additive genetic variance in fitness poses a long-standing question for evolutionary geneticists. A new theoretical paper by Connallon & Czuppon examines the effect of random genetic drift and temporal fluctuations in fitness on loci maintained by balancing selection. It suggests ways in which substantial additive variance can be maintained, by causing loci to depart from their equilibria under selection alone.

Citation format

CHARLESWORTH, Brian. How is variation in fitness maintained? EVOLUTION, 2026, 80(5): 1122–1124.