Medicine

V. Svintsitsky, M. Yegorov, E. Stakhovsky, Y. Vitruk, O. Renkas, A. Svintsitska, O. Bakai, L. Taran, N. Bankovska

2026.3.5Experimental Oncology

DOI: 10.15407/exp-oncology.2025.04.467

tlooto Summary

Despite the fact that in most cases of advanced stages ofС, chemoradiotherapy is effectively used, in some selected cases, surgery may be leading and effective if the operation is performed in a radical manner.

Abstract

BACKGROUND Cervical cancer (СС) continues to be the leading cancer pathology affecting women of both young and older ages. In the advanced stages of СС, the choice of treatment typically favors chemoradiotherapy. However, in a number of cases, radical surgery may be the only effective treatment. Th s issue requires further analysis. MATERIALS AND METHODS Five selected cases of the advanced СС (stages IIa-IVa) that required non-standard treatment are presented. RESULTS In all presented cases, the radical surgical treatment had an undeniable immediate curative effect. On follow-up, two patients are alive without any evidence of the disease; two patients died from disease progression and one patient is still receiving treatment for bone recurrence. CONCLUSIONS Despite the fact that in most cases of advanced stages of СС, chemoradiotherapy is effectively used, in some selected cases, surgery may be leading and effective if the operation is performed in a radical manner. Important in this regard are the clinical experience, high level of surgical skills, presence of a multidisciplinary team, and the technical equipment of the medical center for performing such operations.

Citation format

SVINTSITSKY, V., et al. NON-STANDARD STRATEGIES IN THE TREATMENT OF ADVANCED CERVICAL CANCER: A CASE SERIES. Experimental Oncology, 2026, 47 4: 467–477.