Jasiya Qadir, S. Majid, S. Lone, Mumtaz-Din Wani, M. Khan
tlooto Summary
The spectrum of ARID1A variants in exon-9, its mRNA expression in CRC tissues and potential correlations with clinicopathological parameters are investigated.
Abstract
OBJECTIVE ARID1A has emerged as a pivotal tumour suppressor gene, essential to chromatin remodelling and gene regulation. In colorectal cancer (CRC), dysregulated ARID1A gene expression triggers uncontrolled cellular growth and chemoresistance. This study investigates the spectrum of ARID1A variants in exon-9, its mRNA expression in CRC tissues and potential correlations with clinicopathological parameters.
Citation format
QADIR, Jasiya, et al. The underlying influence of ARID1A under expression in the pathogenesis of colorectal cancer. Turk Onkoloji Dergisi-Turkish Journal of Oncology, 2026: 1–9.