BiologyMedicine

John A. Lesku, Hannah Elmes

2026.3.1TRENDS IN NEUROSCIENCES

DOI: 10.1016/j.tins.2026.02.005

tlooto Summary

Sleep is characterized in two of the simplest neuron-bearing animals to reveal that DNA, damaged while awake, is repaired during sleep, providing evidence for an evolutionarily ancient sleep function.

Abstract

Sleep is widespread across animal species, yet its functions remain enigmatic. In a recent study, Aguillon, Harduf et al. characterize sleep in two of the simplest neuron-bearing animals to reveal that DNA, damaged while awake, is repaired during sleep. In doing so, the authors provide evidence for an evolutionarily ancient sleep function.

Citation format

LESKU, John A.; ELMES, Hannah. DNA repair as a core function of sleep. TRENDS IN NEUROSCIENCES, 2026, 49(4): 249–250.