PsychologyMedicine

L. Pelizza, E. Leuci, E. Quattrone, M. Occhionero, A. Biancalani, Derna Palmisano, S. Pupo, G. Paulillo, Clara Pellegrini, P. Pellegrini, M. Menchetti

2026.4.8Asia-Pacific Psychiatry

DOI: 10.1111/appy.70021

Abstract

ABSTRACT Disorganization is under‐treated in early psychosis. We aimed at exploring clinical factors potentially improving disorganization in individuals at Clinical High Risk for Psychosis (CHR‐P) across 2 years of follow‐up. About 180 participants completed the GAF and the PANSS. Longitudinally, 111 (61.7%) individuals had a decrease in disorganization. Significant associations of this improvement were with shorter duration of untreated illness, higher improvement in negative symptoms, and antipsychotic prescription.

Citation format

PELIZZA, L., et al. Clinical factors influencing improvement in disorganization in clinical high‐risk for psychosis: Preliminary findings from a 2‐year follow‐up. Asia-Pacific Psychiatry, 2026, 18(2): e70021.