Fascitis necrotizante facial en contexto de agranulocitosis por metamizol: manejo de una complicación poco frecuente

A case is presented of a British patient who developed agranulocytosis secondary to metamizole use, which was complicated by facial necrotizing fasciitis caused by Pseudomona aeruginosa . Metamizole-induced agranulocytosis is a rare but serious adverse reaction, reported to be more frequent in populations with a possible genetic predisposition. The resulting profound neutropenia predisposes patients to severe opportunistic infections, with Pseudomona aeruginosa being a particularly aggressive pathogen in this setting. The clinical course was rapidly progressive, requiring intensive therapeutic management with broad-spectrum antibiotics and surgical intervention. This case highlights the need for cautious use of metamizole, especially in patients of British origin, as well as the importance of aggressive management once the condition develops and the potential for reconstructive options following resolution of the disease.