Materials ScienceEngineeringMedicine

Manickaraj Karuppusamy, Sivasubramanian Palanisamy, M. Gurusamy, V. Balasubramanian, Manivannan Jayamani, S. L. Sankar, K. Sundararajan, G. Sivanantham, Syed Kashif Ali, Murugesan Palaniappan, Mezigebu Belay, Mohamed Abbas

2026.3.1GLOBAL CHALLENGES

DOI: 10.1002/gch2.70101

Abstract

The field of biomimetic and bioinspired materials has progressed rapidly by drawing inspiration from nature's intricate structures and multifunctional systems in order to address pressing challenges in modern engineering. This review critically examines the mechanical performance of these materials, focusing on their hierarchical design principles, synthesis strategies, and versatility of application. Natural exemplars such as nacre, spider silk, and bone are emphasized, as their structural efficiency and functional adaptability have informed the development of synthetic analogues with superior strength, toughness, flexibility, and lightweight characteristics. The review also highlights advanced fabrication methods, such as additive manufacturing and precision chemical synthesis, which have enabled researchers to replicate the complexity of nature with ever‐greater accuracy. Key case studies demonstrate how bioinspired strategies have been translated into high‐performance materials for use in the aerospace, construction, and biomedical sectors. The review also discusses challenges related to scalability, reproducibility, and industrial integration. Finally, the review outlines emerging interdisciplinary approaches that are set to further enhance the mechanical properties and practical relevance of biomimetic materials, establishing them as transformative solutions for the next generation of engineering systems.

Citation format

KARUPPUSAMY, Manickaraj, et al. Biomimetic and bioinspired materials: Design strategies, mechanical properties, and engineering applications—a review. GLOBAL CHALLENGES, 2026, 10(3): e70101.