Gene therapy for hemophilia: psychological perspectives on decision making and treatment outcomes.

Hemophilia is a rare bleeding disorder that can significantly impact various aspects of life. In recent years, a number of treatments have become available for persons with hemophilia. One of the most novel treatments, now accessible to adults in a few countries, is gene therapy. Due to its nature as a single-shot treatment, this treatment regimen not only influences physical health but also exerts a profound impact on psychological well-being. This review provides a comprehensive overview of the psychological outcomes associated with gene therapy and explores the role of psychologists at different stages of the treatment process. Additionally, it examines various measurement tools that can be used to assess the psychological aspects of individuals undergoing gene therapy.