Medicine

Rita Alvelos, P. Santos, Mariana Sebastião, Catarina Tavares, Inês B. Rua, Caetano Joana Serra-, Rita Cardoso, I. Dinis, Alice Mirante

2026.3.1Pediatric Endocrinology, Diabetes and Metabolism

DOI: 10.5114/pedm.2026.159708

Abstract

INTRODUCTION: Type 1 diabetes mellitus (T1D) is one of the most common chronic diseases in childhood, with its incidence increasing globally. The coronavirus disease 2019 (COVID-19) pandemic has been associated with an increase in severity of cases of diabetic ketoacidosis. AIM OF THE STUDY: Type 1 diabetes mellitus (T1D) is one of the most common chronic diseases in childhood, with its incidence increasing globally. The coronavirus disease 2019 (COVID-19) pandemic has been associated with an increase in severity of cases of diabetic ketoacidosis. MATERIAL AND METHODS: A retrospective cohort study was conducted, using patients' clinical records, between March 2016 and March 2024. The sample was divided in three groups: pre-pandemic (March 2016 to March 2020), pandemic (March 2020 to March 2021), and post-pandemic (March 2021 to March 2024). RESULTS: A retrospective cohort study was conducted, using patients' clinical records, between March 2016 and March 2024. The sample was divided in three groups: pre-pandemic (March 2016 to March 2020), pandemic (March 2020 to March 2021), and post-pandemic (March 2021 to March 2024). CONCLUSIONS: There was an improvement in the post-pandemic period, with a lower severity at presentation. However, the rate of ketoacidosis remained high, and the focus must remain on implementing preventative measures.

Citation format

ALVELOS, Rita, et al. Ketoacidosis in new-onset type 1 diabetes: Return to pre-covid-19 pandemic reality? Pediatric Endocrinology, Diabetes and Metabolism, 2026, 32(1): 32–37.