Pharmaceutical Economics and PolicyPharmaceutical industry and healthcareCapital Investment and Risk Analysis

Ralph B. Siebert, S. Linde, Brandon Norton

2026.2.10JOURNAL OF INDUSTRIAL ECONOMICS

DOI: 10.1111/joie.70020

tlooto Summary

Estimation results provide evidence that transaction‐specific determinants between buyers and sellers exert strong effects on drug prices, and counterfactuals show that group purchasing organizations achieve price reductions that vary across drug classes and that these price reductions primarily depend on buyer price sensitivity.

Abstract

We focus on the determinants of pharmaceutical drug prices. Using data from the Brazilian pharmaceutical market, we find large variations in drug prices across buyers, drug classes, and time periods. Our estimation results provide evidence that transaction‐specific determinants between buyers and sellers (e.g., transaction volume, buyer's loyalty, multiple drug purchases from the same seller) exert strong effects on drug prices. Our counterfactuals show that group purchasing organizations achieve price reductions that vary across drug classes and that these price reductions primarily depend on buyer price sensitivity.

Citation format

SIEBERT, Ralph B.; LINDE, S.; NORTON, Brandon. The determinants of negotiated pharmaceutical prices. JOURNAL OF INDUSTRIAL ECONOMICS, 2026, 74(2): 234–260.