An In Vivo Study to Compare and Evaluate the Antimicrobial Efficacy and pH Change of GC Tooth Mousse and CurodontTM Protect against Streptococcus mutans

Aim and background Dental caries is the most prevalent oral healthcare problem worldwide, especially in pediatric patients. To manage dental caries, typical oral hygiene methods are not enough in many cases. So as to regenerate the tooth structure, remineralization is required. Thus, the aim of this in vivo study was to evaluate the antimicrobial efficacy and salivary pH change with CurodontTM Protect and compare it with an effective remineralizing agent, GC Tooth Mousse.

Materials and methods Both the GC Tooth Mousse (group I) and the CurodontTM Protect remineralizing agent (group II) were tested in an in vivo investigation to determine their antibacterial activity against Streptococcus mutans. Calculating the total viable bacterial colonies by visual inspection with a HiMedia Laboratories Private Limited digital colony counter (LA6660) for statistical analysis allowed us to estimate the antibacterial effectiveness.We used a pocket pH meter to measure the pH of saliva both before and after the treatment. The parametric tests of significance (Wilcoxon paired test/paired t-test) were used for inferential statistics.

Results The presample count of GC Tooth Mousse and CurodontTM Protect was compared and was found to be nonsignificant with a p-value of 0.7. The postsample count of GC Tooth Mousse and CurodontTM Protect, on the other hand, was shown to be statistically significant (p < 0.001). The pre- and post-pH of GC Tooth Mousse and CurodontTM Protect was compared and was found to be nonsignificant with a p-value of 0.1.

Conclusion When tested against S. mutans, the CurodontTM Protect tooth remineralizing agent proved to be more effective than the GC Tooth Mousse remineralizing agent.

How to cite this article Sharma M, Garg P, Vats V, et al. An In Vivo Study to Compare and Evaluate the Antimicrobial Efficacy and pH Change of GC Tooth Mousse and CurodontTM Protect against Streptococcus mutans. Int J Clin Pediatr Dent 2026;19(2):156-163.