Medicine

A. Gorelov, R. Kozlov, I. Andreeva, A. A. Arova, I. Bavykina, M. Grigorovich, E. V. Dovgan, K. D. Ermolenko, O. Zaytseva, S. Zakharenko, V. V. Zelenskaia, S. Zyryanov, N. A. Ilyenkova, Mikhail A. Kachkovskii, T. A. Kogut, E. Kondyurina, V. V. Krasnov, E. Lokshina, Valerij F. Privorotsky, M. Repetskaya, M. F. Rzyankina, S. N. Serikova, O. U. Stetsiouk, D. V. Usenko, L. V. Khanipova, A. M. Shabalov, M. A. Shevyakov, L. V. Yakovleva

2026.2.14TERAPEVTICHESKII ARKHIV

DOI: 10.26442/00403660.2025.12.203481

tlooto Summary

The purpose of the review is to highlight what the authors consider to be the most significant clinical studies on the use of probiotics for preventing antibiotic-associated diarrhea, clostridial diarrhea and pseudomembranous colitis.

Abstract

Probiotics are currently widely used in clinical practice to prevent and treat a wide range of diseases. The purpose of our review is to highlight what we consider to be the most significant clinical studies on the use of probiotics for preventing antibiotic-associated diarrhea, clostridial diarrhea and pseudomembranous colitis. The article also presents the results of studies confirming the efficacy of probiotics in Helicobacter pylori eradication therapy. The review focuses on Linex® Forte, medicinal product containing the combination of Lactobacillus acidophilus (LA-5) and Bifidobacterium animalis subsp. lactis (BB-12).

Citation format

GORELOV, A., et al. [Probiotics' position in clinical practice: Focus on the combination of lactobacillus acidophilus (LA-5) and bifidobacterium animalis subsp. lactis (BB-12). a review]. TERAPEVTICHESKII ARKHIV, 2026, 97 12: 1037–1043.