A. Zouzaf, Hyeon Jong Jeong, S. Santhosh, L. van Baarle, Hyewon Chung, M. Stakenborg, S. Abdurahiman, Yifan Chen, Seung Hyeok Seok, G. Matteoli
tlooto Summary
It is hypothesized that mMφ‐derived ApoE regulates intestinal motility under physiological and stress conditions.
Abstract
Gastrointestinal (GI) motility is controlled by the coordinated activity of enteric neurons, glial cells, and resident muscularis macrophages (mMφs). Apolipoprotein E (ApoE) is highly expressed in mMφs, but its functional role in the gut remains unclear. We hypothesized that mMφ‐derived ApoE regulates intestinal motility under physiological and stress conditions.
Citation format
ZOUZAF, A., et al. Muscularis macrophage‐derived apoe is dispensable for maintaining gut motility in mice. NEUROGASTROENTEROLOGY AND MOTILITY, 2026, 38(2): e70264.