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MedicineChemistry

Novel Glycyrrhizinic Acid Derivative YCY‐20 Inhibits Cerebral Ischemia/Reperfusion Induced Apoptosis via the AGE‐RAGE/MAPK Pathway

Jia Luo, Xue Qin, Jiaxin Chen, Xiushi Yu, Ziyu Liu, Jiyi Lv, Xinhui Pan, Yong Chen, Lili Wei

2026.2.1CNS Neuroscience & Therapeutics

DOI: 10.1002/cns.70792

Abstract

Licorice (Glycyrrhiza spp.), a traditional Chinese herb, contains glycyrrhetinic acid derivatives with neuroprotective properties but limited bioavailability.

Citation format

LUO, Jia, et al. Novel glycyrrhizinic acid derivative YCY‐20 inhibits cerebral ischemia/reperfusion induced apoptosis via the AGE‐RAGE/MAPK pathway. CNS Neuroscience & Therapeutics, 2026, 32(2): e70792.