PsychologyMedicine

Brandon P. Miller, James G Murphy, J. MacKillop, Laura E. Martin, M. Amlung

2026.2.2Journal of Studies on Alcohol and Drugs

DOI: 10.15288/jsad.25-00300

Abstract

OBJECTIVE Murphy et al. (2014) found that university students with a family history (FH) of alcohol problems exhibit a reduced sensitivity of alcohol demand to next-day academic responsibilities. Considering the ongoing replication crisis, the objective of this study was to replicate and extend this research in community adults, including a range of non-academic responsibilities.

METHOD We conducted a secondary analysis of 461 adults who reported past-year alcohol consumption (39% women; mean age = 38.42), recruited from Amazon Mechanical Turk. Participants were coded as FH+ (40%) or FH- (60%) based on reporting if any biological parents or grandparents had a history of alcohol problems. Participants completed alcohol purchase tasks involving a typical drinking situation or next-day responsibility (e.g., work, caregiving). FH status was examined as a moderator of reductions in observed indices of alcohol demand in separate analyses of covariance controlling for participant sex and severity of alcohol misuse.

RESULTS Alcohol demand did not significantly differ by FH status on the no-responsibility APT (ps >.56). Compared to FH- participants, FH+ participants showed a smaller magnitude reduction in the responsibility condition for breakpoint (p =.002, ηp2=.036), Omax (p =.002, ηp2=.041), and Pmax (p =.001, ηp2=.040), and nonsignificant effects for intensity (p =.053, ηp2=.015).

CONCLUSION These findings replicate and extend Murphy et al. (2014) by providing necessary confirmation that FH confers risk for greater alcohol consumption despite upcoming responsibilities. People with a FH of problem drinking may require specific interventions that make the impact of drinking on next-day responsibilities more salient.

Citation format

MILLER, Brandon P., et al. Family history of problem drinking is associated with reduced sensitivity of alcohol demand to next-day responsibilities: A replication and extension. Journal of Studies on Alcohol and Drugs, 2026.