Crystallography and molecular interactionsEnergetic Materials and CombustionForce Microscopy Techniques and Applications

Diyana Dimitrova, Tsvetelina Marinova, Reni Bozhanova, Iliyan Ivanov, D. Bojilov, Gabriel Marc, S. Manolov

2026.2.4Molbank

DOI: 10.3390/m2132

tlooto Summary

This solvent-minimized synthesis of a novel hybrid molecule, N-(4-methoxyphenethyl)-2-propylpentanamide, exemplifies the emerging paradigm of medicinal mechanochemistry, offering an efficient, sustainable route to pharmaceutically relevant amides.

Abstract

Herein, we report the mechanochemical synthesis of a novel hybrid molecule, N-(4-methoxyphenethyl)-2-propylpentanamide. This solvent-minimized synthesis aligns with the principles of Green Chemistry and exemplifies the emerging paradigm of medicinal mechanochemistry, offering an efficient, sustainable route to pharmaceutically relevant amides. The newly synthesized compound was fully characterized by melting point determination, 1H and 13C NMR spectroscopy, infrared (IR) spectroscopy, and mass spectrometry.

Citation format

DIMITROVA, Diyana, et al. N-(4-methoxyphenethyl)-2-propylpentanamide. Molbank, 2026, 2026(1): M2132.