ChemistryMedicine

Synthesis and structure of (7aRS)-4-chloro-6-(4-methylphenyl)-6,7,7a,8-tetrahydro-5H-indeno[5,6-b]furan-5-one, a fused-ring system arising from a new variant of the IMDAV reaction

K. A. Alekseeva, A. Gurbanov, M. S. Grigoriev, Victoria I. Salakhova, E. A. Akishina, Mohammed Hadi Al–Douh, T. Hökelek

2026.1.27Acta Crystallographica Section E-Crystallographic Communications

DOI: 10.1107/s2056989026000629

Abstract

The asymmetric unit of the title compound contains two molecules. In the crystal, C—H⋯O and C—H⋯Cl hydrogen bonds link the molecules into two-dimensional networks, enclosing R33(19), R22(18) and R22(14) ring motifs. C—H⋯π interactions help to consolidate the packing.

Citation format

ALEKSEEVA, K. A., et al. Synthesis and structure of (7ars)-4-chloro-6-(4-methylphenyl)-6,7,7a,8-tetrahydro-5h-indeno[5,6-b]furan-5-one, a fused-ring system arising from a new variant of the IMDAV reaction. Acta Crystallographica Section E-Crystallographic Communications, 2026, 82(2): 212–216.