The Brief Case: Adjudication of discrepant genotypic and phenotypic antimicrobial susceptibility testing results in a patient with Staphylococcus aureus bacteremia

rapid molecular antimicrobial resistance testing, which relies on the identification of well-characterized resistance genes and can be performed directly from clinical specimens (1, 2). On occasion, discrepancies between rapid molecular resistance testing and conventional phenotypic AST can occur. Here, we outline a case of such a discrepancy related to antimicrobial resistance in S. aureus isolated from blood culture, a clinical scenario of high consequence, and review several methods of laboratory adjudication.