Jessica L. Pacheco, Erica J. Hutchins
2026.3.2JOURNAL OF CELL BIOLOGY
tlooto Summary
This issue reveals that epithelial-like neural crest clusters achieve directed chemotaxis through a junction-centered strategy that redistributes polarity, contractility, and traction forces internally.
Abstract
Collective chemotaxis is often viewed through a mesenchymal lens, emphasizing peripheral polarity and force generation. In this issue, Diaz and Mayor (https://doi.org/10.1083/jcb.202507211) reveal that epithelial-like neural crest clusters achieve directed chemotaxis through a junction-centered strategy that redistributes polarity, contractility, and traction forces internally.
Citation format
PACHECO, Jessica L.; HUTCHINS, Erica J. Two ways to move together: Force coordination in collective chemotaxis. JOURNAL OF CELL BIOLOGY, 2026, 225 3(3).