Medicine

Yanyan Dai, Jerry Zhang, Dandan Wu, Ran Chen, Rong Li

2026.2.1INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

DOI: 10.1002/jdn.70106

tlooto Summary

This study is designed to characterize the clinical phenotype of neurodevelopmental disorder in a cohort of seven children associated with variants in the HUWE1.

Abstract

The HUWE1 gene plays a crucial role in mediating embryonic development as well as the differentiation and proliferation of neural cells. Variants in the HUWE1 are closely associated with intellectual developmental disorder. This study is designed to characterize the clinical phenotype of neurodevelopmental disorder in a cohort of seven children associated with variants in the HUWE1.

Citation format

DAI, Yanyan, et al. Novel huwe1‐related neurodevelopmental disorder: Genotypic and phenotypic expansion. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, 2026, 86(1): e70106.