Tao Jun, Hongjian Li, Wenqi Feng
2026.2.26JOURNAL OF REHABILITATION MEDICINE
Abstract
reports the association between higher pre-test heart rate and a higher Buffalo Concussion Treadmill Test (BCTT) symptom threshold with a coefficient of 0.34 and a 95% confidence interval of 0.17 to −0.50 (1). The interval is internally inconsistent; the bounds are reversed and the sign is incompatible with the stated direction. In the main text and Table III, the same effect is reported as 0.17 to 0.50 with p < 0.001, which is coherent and indicates a positive association (1). A concise erratum that corrects the abstract and checks for internal agreement across sections would prevent confusion and preserve confidence in the statistical reporting. Second, time since injury differs between groups yet is omitted from the logistic model relating the Rivermead Post Concussion Symptoms Questionnaire (RPQ) score to EI. Table I indicates a meaningful gap in months since injury (6.95 vs 9.44; p = 0.010) between EI and exercise-tolerant participants (1). Because recovery after traumatic brain injury is time dependent, not adjusting for this covariate risks attributing the effect of injury chronicity to symptom burden. The reported odds ratio of 1.07 per RPQ point may therefore be inflated by recovery stage. Including months since injury as a covariate, and verifying the result in stra - tified or sensitivity analyses, would clarify whether RPQ independently predicts EI. Third, the linear regression of the BCTT symptom thres- hold uses only the 81% who were EI and excludes the 19% who completed the test without symptom exacerbation (1). For these exercise-tolerant participants, the threshold lies at or beyond the stopping criterion and is unobserved, which makes the outcome right censored. Discarding them can bias coefficients for predictors such as pre-test heart rate and anxiety and narrows applicability to the full clinic po - pulation. A straightforward remedy is to treat the threshold as a censored outcome and analyse it with Tobit or survival
Citation format
JUN, Tao; LI, Hongjian; FENG, Wenqi. Commentary on: Exploring exercise intolerance in adult patients with persistent post-concussion symptoms after mild traumatic brain injury. JOURNAL OF REHABILITATION MEDICINE, 2026, 58: jrm45050.