I. S. Kirbis, Ivana Kholová, H. Huhtala, M. Fležar, R. Roque, Heli-Hakso Mäkinen, Miisa Litmanen, D. Vrdoljak-Mozetič, Suzana Harabajsa, E. Hewer, E. Bresaola, Lia van Zuylen-Manders, Pawel Schubert, M. Praça, E. Rossi, P. Bode, Laetitia Lacoste-Collin, J. Barizzi, V. Fiorentino, T. Hedegaard, Sietske van der Meulen, Ute Engel, Iris Timmer, T. Turkmenoglu, J. Vidak, E. Vigliar, S. Manso, Jamal Musayev, G. Barkan, María D Lozano, L. Ivkovski, B. V. van Hemel, L. Carsana, C. di Tonno, Birgit Weynand, Tania Labiano, B. Cochand-Priollet
2026.2.25CYTOPATHOLOGY
tlooto Summary
Evaluating the cellularity of routinely prepared CBs across different preparation methods, laboratories and sample types found formalin‐fixed, paraffin‐embedded cell blocks to have low cellularity.
Abstract
Formalin‐fixed, paraffin‐embedded (FFPE) cell blocks (CBs) are widely used for processing cytology specimens, but preparation methods remain variable and non‐standardised. Low cellularity is a common limitation that may compromise diagnostic utility. This study aimed to evaluate the cellularity of routinely prepared CBs across different preparation methods, laboratories and sample types.
Citation format
KIRBIS, I. S., et al. Cellularity of routinely prepared cell blocks: Insights from an international study. CYTOPATHOLOGY, 2026, 37(3): 214–221.