Operationalizing the WHO Six Building Blocks Framework for a School-Based Digital Mental Health Platform: A Pilot Implementation Study in Thailand.

Adolescent depression is a growing concern in Thailand, yet school-based services remain fragmented. This study developed and evaluated "TeenTalk Mender," a digital platform guided by the WHO Six Building Blocks framework to support school health services. A 12-week quasi-experimental pilot was conducted with 55 secondary students, stratified into "general" and "at-risk" groups based on patient health questionnaire for adolescents scores. Feasibility, user satisfaction (technology acceptance model), and depression scores were assessed. The platform achieved a 100% engagement rate. Satisfaction scores were high across both groups with no significant difference (p > 0.05), indicating successful universal design. Although depression scores in the at-risk group decreased, the change was not statistically significant (p = 0.113). The platform demonstrates high feasibility and acceptability, serving as an effective digital tool to connect adolescents with school nurses. Future research should involve larger-scale trials to assess clinical efficacy.