ChemistryMedicine

1,3,4-Oxadiazole derivatives: targeting multiple bacterial pathways.

Pankaj Gupta, Sangeeta Verma, Rakesh Narang, Bhupesh Sharma, Vikramjeet Singh, S. Lal

2026.2.25RSC Medicinal Chemistry

DOI: 10.1039/d5md01139f

tlooto Summary

Recent advances in SAR analysis and various binding modes of 1,3,4-oxadiazole derivatives as antibacterial agents are consolidated and will be beneficial for researchers in the development of novel antibacterial molecules based on the 1,3,4-oxadiazole moiety.

Abstract

Antimicrobial resistance (AMR) has emerged as a major worldwide issue in the effective management of infectious diseases. This problem prompted researchers worldwide to develop new therapeutic agents that target both...

Citation format

GUPTA, Pankaj, et al. 1,3,4-Oxadiazole derivatives: Targeting multiple bacterial pathways. RSC Medicinal Chemistry, 2026, 17(4): 1867–1887.