Multiple organ failure syndrome in the neonatal period in preterm newborns from monochorionic twins (literature review)

This literature review systematizes current knowledge about the epidemiology and clinical features of newborns from multiple pregnancies with monochorionic placentation. The specific complications characteristic of this group are highlighted, namely twin-twin transfusion syndrome, anemia-polycythemia syndrome and selective fetal growth retardation syndrome. Modern approaches to the diagnosis and prognosis of multiple organ failure syndrome in this category of patients, such as the nSOFA and NEOMOD scales, are considered. However, these systems do not have sufficient flexibility to assess the health status of this group of patients, which underscores the need for further research on predictors of the development of multiple organ failure syndrome. In particular, it is relevant to study the acid-base state and gas homeostasis of blood in the neonatal period in newborns from monochorionic twins, which is an urgent task for optimizing perinatal care.