Exploring the Associations Between Affective and Non‐Affective Cognitive Domains in Mood Disorders and Healthy Controls Using Network Analysis

Cognitive impairment is a core feature of mood disorders that contributes to reduced functioning and poorer prognosis, thereby emerging as an important treatment target. Persistent trait‐related impairments present within both affective and non‐affective cognition. Nevertheless, the relationship between affective and non‐affective cognitive domains remains unclear, including whether impairments in emotion regulation and facial expression recognition are secondary to deficits in non‐affective cognition. Mapping out the hierarchical structure of affective and non‐affective cognitive domains may elucidate core cognitive impairments that represent the most relevant treatment targets.