Medicine

Pretreatment Cytokine Signatures as Candidate Biomarkers for JAK Inhibitor Response in Anti‐MDA5 Dermatomyositis–Related Interstitial Lung Disease: A Pilot Study

Haruna Matsuo, T. Koga, T. Shimizu, H. Ide, Serina Koto, Kanako Kojima, Y. Fujita, M. Okamoto, A. Takatani, Takahisa Suzuki, Yuta Matsushita, A. Kawakami

2026.2.1ACR Open Rheumatology

DOI: 10.1002/acr2.90002

Abstract

To evaluate the clinical characteristics and serum cytokine profiles of patients with anti‐MDA5 antibody–positive dermatomyositis with interstitial lung disease (MDA5+ DM‐ILD) treated with JAK inhibitors and to compare survivors and nonsurvivors.

Citation format

MATSUO, Haruna, et al. Pretreatment cytokine signatures as candidate biomarkers for JAK inhibitor response in anti‐mda5 dermatomyositis–related interstitial lung disease: A pilot study. ACR Open Rheumatology, 2026, 8(2): e90002.