AI in cancer detectionColorectal Cancer Screening and DetectionAdvanced Neural Network Applications

Zijian Lin, Zhezhen Cai, Jiubing Guo

2026.2.20Journal of Mechanics in Medicine and Biology

DOI: 10.1142/s0219519426400312

tlooto Summary

Experimental results demonstrate that MV2I SwinNet consistently outperforms classical convolutional neural networks, Transformer-based models, and existing hybrid approaches, indicating that the proposed method provides an effective and reliable solution for computer-aided gastric cancer diagnosis.

Abstract

Timely and accurate diagnosis of gastric cancer is critical for effective treatment planning and improved patient outcomes. Histopathological examination remains the gold standard for diagnosis; however, existing image classification models often struggle to simultaneously capture fine-grained local tissue patterns and long-range contextual information, which may limit their diagnostic accuracy. To address this issue, we propose a hybrid image classification framework: MobileNetV2-Inception-Swin Transformer based Hybrid Network, termed MV2I SwinNet in short, where MV2I denotes the integration of MobileNetV2-based modules and an Inception-inspired multi-scale design. lightweight convolutional feature extraction with a Swin Transformer to jointly model local structural details and global contextual dependencies in gastric histopathological images. Specifically, redesigned MV2 Inception blocks are employed to enhance multi-scale feature representation with limited computational overhead, while a hierarchical Swin Transformer is used to capture global contextual information. Experimental results on the public GasHisSDB dataset demonstrate that MV2I SwinNet consistently outperforms classical convolutional neural networks, Transformer-based models, and existing hybrid approaches. These results indicate that the proposed method provides an effective and reliable solution for computer-aided gastric cancer diagnosis.

Citation format

LIN, Zijian; CAI, Zhezhen; GUO, Jiubing. MV2I swinnet: A deep learning based image classification network for gastric tissue pathology images. Journal of Mechanics in Medicine and Biology, 2026, 26(03).