Epidemiology of Helicobacter pylori infection in the Russian Federation from 1990 to 2023: a systematic review

H. pylori affects more than half of the world's population and is associated with chronic gastritis, which can progress to serious complications such as peptic ulcer disease, gastric cancer, and MALT lymphoma. Epidemiological studies allow for the assessment of the level and changes in the prevalence of H. pylori infection. This paper addresses the results of H. pylori prevalence studies conducted in the Russian Federation. The high prevalence of H. pylori in adults and children in the 1990s and its significant reduction in recent years are reported. The prevalence of infection in adults is greater than in children in all time intervals studied, which is probably associated with poorer sociohygienic conditions in childhood in previous generations. The results of epidemiological studies on the prevalence of H. pylori are heterogeneous and depend on the time of the study, the region, and diagnostic method. The prevalence of H. pylori infection as determined by the 13C urea breath test has been found to be lower than that observed in serological studies. This discrepancy is attributed to the greater specificity of the breath test in detecting current infection KEYWORDS: Helicobacter pylori, epidemiological study, prevalence of H. pylori, Helicobacter infection, Russian Federation. FOR CITATION: Bordin D.S., Kuznetsova E.S., Stauver E.E., Nikol'skaya K.A., Chebotareva M.V., Voynovan I.N., Neyasova N.A. Epidemiology of Helicobacter pylori infection in the Russian Federation from 1990 to 2023: a systematic review. Russian Medical Inquiry. 2024;8(5):260–267 (in Russ.). DOI: 10.32364/2587-6821-2024-8-5-3.