Precision Medicine Paradigms in Allergic Rhinitis: Navigating Immunotherapy and Digital Healthcare

ABSTRACT Introduction This review examines the impact of allergic rhinitis (AR) on health, emphasizing precision medicine as a transformative approach, with AR treatments to individual factors and explores allergen immunotherapy (AIT) as a disease-modifying strategy, stressing adherence to 2019 ARIA care pathways. The role of digital technologies and mobile health tools in supporting patient-centered care is emphasized. Challenges and future prospects, including improved AIT adherence and novel biomarkers, are addressed. Area covered This article provides a comprehensive overview of personalized medicine, encompassing its definition, key components, and transformative impact on healthcare. It explores the role of next-generation sequencing in advancing personalized medicine, highlighting potential benefits and challenges in healthcare system implementation. Additionally, the article explores the underlying mechanisms of allergic rhinitis, the efficacy of allergen immunotherapy, and the utilization of mobile apps to improve adherence and self-care. Expert opinion It also delves into the pathophysiology of AR and the use of innovative technologies and advancements in the AR to improve patient care. The insights presented in this article are valuable for understanding the evolving landscape of precision medicine and its impact on AR.