Medicine

Pedro Fraiman, Kaliny Oliveira Peixoto, Rodrigo Alencar E Silva, Clécio de Oliveira Godeiro Júnior

2026.4.24PRACTICAL NEUROLOGY

DOI: 10.1136/pn-2026-005176

tlooto Summary

This case highlights paraneoplastic striatal encephalitis as an important cause of late-onset chorea and red flags such as subacute progression, systemic symptoms and characteristic MR imaging changes should prompt early investigation for neuronal antibodies and malignancy.

Abstract

Tubular aggregate myopathies comprise a rare group of disorders with characteristic pathological findings and heterogeneous phenotypes, including myasthenic syndrome. We describe a patient with tubular aggregate myopathy who presented with fatiguable weakness improving with pyridostigmine, respiratory involvement and possible cardiac manifestations. We highlight the utility of muscle biopsy in atypical myasthenic syndrome.

Citation format

FRAIMAN, Pedro, et al. Late-onset subacute chorea. PRACTICAL NEUROLOGY, 2026, 24: 137–140.