MedicineEngineering

R. Siboni, J. Sergheraert, L. Thoraval, Christine Guillaume, S. Gangloff, Xavier Ohl, J. Braux, F. Velard

2025.1.1Journal of Tissue Engineering and Regenerative Medicine

DOI: 10.1155/term/7357277

tlooto Summary

The optimisation and validation of such a preclinical model, considering the results obtained after the use of biomaterials as a substitute for bone grafting, could lead to simplifying the surgical procedure and enhance the clinical results.

Abstract

Background: The induced membrane (IM) preclinical models have been described in small animals, but few studies have looked at bone regeneration achievement. The optimisation and validation of such a preclinical model, considering the results obtained after the use of biomaterials as a substitute for bone grafting, could lead to simplifying the surgical procedure and enhance the clinical results.

Citation format

SIBONI, R., et al. Optimisation and validation of an induced membrane technique model to assess bone regeneration in rats. Journal of Tissue Engineering and Regenerative Medicine, 2025, 2025.