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Association of polymorphisms of genes in neurotransmitter systems of the brain with the risk of developing mental disorders in children left without parental care

E. A. Bodagova, Nikolai V. Govorin, V. A. Mudrov

2025.4.3Research Results in Biomedicine

DOI: 10.18413/2658-6533-2025-11-1-1-0

Abstract

. . , , , , . : TPH1, MAOA, HTR2A, DRD4, COMT, DBH, DRD2 , . : 516 2018 . 2020 ., - : rs1800532 TPH1(A218C), rs6323 MAOA (R297R), rs6313 HTR2A (T102C), rs1800955 DRD4 (C-521T), rs4680 COMT (G472A), rs1611115 DBH (C-1021T), rs1800497 DRD2 (Taq1A), , . . - - ( 2 ). <0,05.: - rs1800532 TPH1(A218C) , (p=0,006). rs4680 COMT (G472A) / rs1800497 DRD2 (Taq1A) : , (p=0,01 p=0,003 ).: rs1800532 TPH1(A218C), rs4680 COMT (G472A) rs1800497 DRD2 (Taq1A) 1,65 .

Citation format

BODAGOVA, E. A.; GOVORIN, Nikolai V.; MUDROV, V. A. Association of polymorphisms of genes in neurotransmitter systems of the brain with the risk of developing mental disorders in children left without parental care. Research Results in Biomedicine, 2025.