Medicine

Yuichiro Matsuo, A. Okada, Hideo Yasunaga

2026.1.3JOURNAL OF INTERNAL MEDICINE

DOI: 10.1111/joim.70063

tlooto Summary

An active comparator new user cohort design was employed, using acetaminophen as the active comparator, using acetaminophen as the active comparator.

Abstract

Previous observational studies have reported an increased risk of venous thromboembolism (VTE) among non‐steroidal anti‐inflammatory drug (NSAID) users compared with non‐users. However, these studies may have been subject to bias due to unmeasured confounders related to patient conditions requiring NSAIDs. We employed an active comparator new user cohort design, using acetaminophen as the active comparator.

Citation format

MATSUO, Yuichiro; OKADA, A.; YASUNAGA, Hideo. Non‐steroidal anti‐inflammatory drugs versus acetaminophen and risk of venous thromboembolism: An active comparator new user cohort study. JOURNAL OF INTERNAL MEDICINE, 2026, 299(3): 381–397.