Soken Go, Natsumi Morishita, Mika Takeshita, Misako Murakami, Saori Minami, Wakako Matsumoto, Kanako Hayashi, Ryou Takahashi, Yusuke Watanabe, Naoko Saito, Koko Ohno, A. Kasuga, Shinichiro Morichi, Yu Ishida, C. Ishii, Naoko Kinjo, Gaku Yamanaka
2026.1.1PEDIATRIC NEUROLOGY
tlooto Summary
A generalist-deliverable BPS model was associated with sustained improvement in CDH outcomes, even in the absence of subspecialty resources, and this pragmatic framework may support individualized, function-centered care for pediatric CDH in real-world settings.
Abstract
BACKGROUND Chronic daily headache (CDH) in youth is a functionally disabling and diagnostically heterogeneous condition that often requires multifaceted intervention. Real-world care is frequently fragmented-either limited to pharmacologic management or constrained by limited access to behavioral services. We evaluated the effectiveness of a generalist-deliverable bio-psycho-social (BPS) management model for children and adolescents with CDH, addressing both pharmacologic and contextual factors in the absence of subspecialty mental health services.
METHODS This retrospective, single-center observational study included 37 pediatric patients diagnosed with CDH according to ICHD-3 criteria. All participants received a structured BPS model delivered by general pediatricians. The model comprised (1) feature-guided pharmacologic treatment, (2) narrative-based psychosocial dialog, and (3) gradual school reintegration. Headache frequency, school attendance, and Pediatric Migraine Disability Assessment-assessed disability were evaluated at baseline, 6 months, and 24 months.
RESULTS By 6 months, only 13.5% of patients met CDH criteria; by 24 months, this decreased to 5.4%. Headache frequency, school attendance, and disability scores improved significantly (P < 0.001 for all). Improvements occurred across diagnostic subtypes and were not solely dependent on pharmacologic treatment, underscoring the contribution of nonpharmacologic components. Functional recovery-particularly school attendance-often lagged behind symptom resolution.
CONCLUSIONS A generalist-deliverable BPS model was associated with sustained improvement in CDH outcomes, even in the absence of subspecialty resources. This pragmatic framework may support individualized, function-centered care for pediatric CDH in real-world settings.
Citation format
GO, Soken, et al. A generalist-deliverable bio-psycho-social model for pediatric chronic daily headache: A 24-month retrospective study. PEDIATRIC NEUROLOGY, 2026, 177: 77–84.