Medicine

When HIV pays the price: Fitness costs behind lenacapavir resistance.

M. Choudhary, Johanthan Z. Li

2026.1.7Science Translational Medicine

DOI: 10.1126/scitranslmed.aed6475

Abstract

HIV can take several mutational pathways to become resistant to lenacapavir, each with distinct resistance and fitness profiles (Pennetzdorfer et al., this issue).

Citation format

CHOUDHARY, M.; LI, Johanthan Z. When HIV pays the price: Fitness costs behind lenacapavir resistance. Science Translational Medicine, 2026, 18 831(831): eaed6475.