Combined hyperbaric oxygen therapy and repetitive transcranial magnetic stimulation in depression and PTSD: future perspectives

share overlapping mechanisms of action. This suggests that their combination could have synergistic effects in the treatment of MDD and PTSD. Furthermore, both are non-invasive and safe therapeutic approaches. However, data on the incidence of adverse effects associated with their combination therapy remain insufficient. Additional studies are needed to achieve a higher level of evidence-based medicine, but this combination therapy appears to be promising for future clinical practice.