Davide Grillo, Mattia Cecconi, Gianluca Ossola, Alessia Stefanello, Silvia Ciceri, V. Romano, M. Zitti, Giacomo Basso, Rudy Gasparin Pavan, Michele Perrucchini, Giuseppe Dallapellegrina, Gabriele Carbonetti, F. Pagani, C. Colombo, Camilla Vignozzi, Nicolò Tassan Viol, A. Lahmar, I. Geraci, S. Bargeri, Eugenio Santoro, B. Cieślik, Silvia Zangarini, Stefano Bargellesi, P. Kiper
tlooto Summary
A scoping review is performed to systematically explore whether and how exercise is provided by DTx for preventing and managing NCDs, and which of those provide exercise therapy as intervention.
Abstract
INTRODUCTION Physical activity is widely recognised as effective in preventing and managing non-communicable diseases (NCDs). Digital health innovations can facilitate the delivery of physical exercise programs for this population. Digital therapeutics (DTx) could transform healthcare delivery, including how digital exercise therapy is provided. We aim to perform a scoping review to systematically explore whether and how exercise is provided by DTx for preventing and managing NCDs.
METHODS This protocol follows the Joanna Briggs Institute (JBI) methodology for scoping reviews and is reported according to JBI best practice guidance. A comprehensive search strategy will be performed in MEDLINE, CINAHL, Cochrane, PEDro and Google to identify existing DTx for preventing and treating NCDs, and which of those provide exercise therapy as intervention. Key data of the included studies will be charted descriptively and supplemented by summary tables.
ETHICS AND DISSEMINATION This scoping review does not require ethics review and approval. Our target audience for this review will be DTx manufacturers, health policy makers, clinicians, researchers, patients and other relevant stakeholders, in order to highlight gaps and potential of physical exercise provided by DTx. Results will be disseminated through peer-reviewed publications, online platforms and conference presentations.
PROTOCOL REGISTRATION NUMBER https://osf.io/fyqt8.
Citation format
GRILLO, Davide, et al. Is exercise a medicine provided by digital therapeutics for people with ncds? A scoping review protocol. Disability and Rehabilitation-Assistive Technology, 2026, 21(4): 1–15.