Thi Thanh Ngan Nguyen, M. M. N. Tun, Thi Bich Hau Vu, Thi Thu Thuy Nguyen, Vu Mai Phuong Hoang, L. Nguyen, Trong Lan Phan, D. Dang, Muhareva Raekiansyah, Ryosuke Suzuki, Jean Claude Balingit, Yuki Takamatsu, C. Buerano, Takeshi Urano, Thi Quynh Mai Le, F. Hasebe, Kouichi Morita
2026.1.1VIRUS RESEARCH
tlooto Summary
Broad spectrum of ADE was seen across DENV serotypes, ZIKV, and JEV, with implications for vaccines and prior exposure influences neutralization and ADE.
Abstract
Highlights • Prior exposure influences neutralization and ADE, with implications for vaccines.• Broad spectrum of ADE was seen across DENV serotypes, ZIKV, and JEV.• JEV-induced ADE was detected in all DENV patients, with similar levels in DWWS and DWOWS.• ZIKV-ADE was observed mainly in secondary DENV infections, elevated in DWWS.
Citation format
NGUYEN, Thi Thanh Ngan, et al. Implications of immune responses to DENV, JEV, and ZIKV infections for cross-reactivity and considerations for vaccine evaluation. VIRUS RESEARCH, 2026, 364: 199689.