Carnosic Acid Mediates Production of Reactive Oxygen Species to Regulate Mitogen‐Activated Protein Kinase Pathway Phosphorylation and Induce Apoptosis in Human Breast Cancer Cells

Reactive oxygen species (ROS) can induce cancer cell apoptosis, which plays a crucial role in breast cancer therapy. Carnosic acid (CA) exerts an anti‐tumor effect via generating ROS or activating the mitochondria‐related apoptosis pathway in vitro and in vivo. The deoxy‐glucose derivative CN5DG labeled with 99mTc can be used for breast cancer imaging and evaluating the therapeutic efficacy of CA.