Evaluating the Effectiveness of Early Genetic Screening for Fanconi Anemia in High‐Risk Pediatric Populations

Fanconi anemia (FA) is the most prevalent inherited disorder leading to bone marrow failure, resulting from a rare autosomal recessive genetic condition that affects all three types of blood cells. A key characteristic of FA is the body's heightened sensitivity to DNA‐damaging agents, particularly those that induce crosslinking, which serves as an important diagnostic marker. Children at higher risk—such as those with unexplained growth delays, congenital defects, or a family history of FA—can significantly benefit from genetic testing.