Fangzhen Shan, Shuntao Liang, Youwen Zhang, Wei Wu, Guangxia Yang, Mei Yan, Xue-mei Zhang, Yu-Run Miao, Linlin Liu, Jingjing Cai, Zhitao Shi, Bangdong Liu, Nannan Zhang
2026.1.1Clinical Respiratory Journal
tlooto Summary
Thoracic SMARCA4‐deficient undifferentiated tumors (SMARCA4‐UT) are rare and aggressive epithelioid neoplasms characterized by the loss of the SMARCA4 gene and exhibit a dismal prognosis.
Abstract
Thoracic SMARCA4‐deficient undifferentiated tumors (SMARCA4‐UT) are rare and aggressive epithelioid neoplasms characterized by the loss of the SMARCA4 gene. These tumors are typically diagnosed at advanced stages and exhibit a dismal prognosis. Currently, there are no standardized treatment protocols or approved targeted therapies.
Citation format
SHAN, Fangzhen, et al. Smarca4‐deficient undifferentiated thoracic tumor: Clinical features and prognosis of a case series and literature review. Clinical Respiratory Journal, 2026, 20(1): e70168.